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FITC - anti mouse CD11c - Clone N418

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FITC - anti mouse CD11c - Clone N418

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FITC - anti Mouse CD11c - N418

Reference	Size	Price	Quantity
MO11CF(V25)	25 µg	40,00 € tax excl.	The minimum purchase order quantity for the product is 1
MO11CF(V100)	100 µg	81,00 € tax excl.	The minimum purchase order quantity for the product is 1
MO11CF(V500)	500 µg	105,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

MO11CF(V25)

25 µg

40,00 € tax excl.

MO11CF(V100)

100 µg

81,00 € tax excl.

MO11CF(V500)

500 µg

105,00 € tax excl.

Product Description

Clone: N418
Isotype: Armenian Hamster IgG
Tested Applications: Flow Cytometry
Conjugated: FITC
Concentration: 0.5 mg/ml
Immunogen: Mouse Dendritic Cells
Species Reactivity: Mouse
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage:
Presentation: Liquid
Storage Instruction: Store in the dark at 2-8 °C

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Large description: CD11c clone N418 is specific for CD11c, a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c, a member of the leukointegrin family, is expressed prominently on tissue macrophages and dendritic cells and binds to complement fragment (iC3b), provisional matrix molecules (fibrinogen), and the Ig superfamily cell adhesion molecule, ICAM-1. CD11c has been proposed to function in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T cell proliferation by Langerhans cells2. The N418 epitope is detected only on dendritic cells and is not present on peritoneal macrophages, anti-immunoglobulin induced B lymph oblasts or bulk lymph node cells. The antibody reacts precipitates a 150/90 kDa CD11/CD18 heterodimer. The anti-mouse CD11c mAb N418 blocks CD11c binding to iC3b, ICAM-1, and VCAM-1

Other names: ?X integrin, CR4, and p150
GeneID:
Molecular weight: 150 kD