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CD8/CD56 - IMMUNOSTEP. WE KNOW HOW

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CD8/CD56 - IMMUNOSTEP. WE KNOW HOW

商品详情参考文献相关资料

FITC/ PE - anti Human CD8/CD56 - 143-44, B-A19

Reference	Size	Price	Quantity	Add to cart
8F156PE-50T	50 test	231,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

8F156PE-50T

50 test

231,00 € tax excl.

Product Description

Clone: 143-44, B-A19
Isotype: IgG1, IgG1
Tested Applications: FCM
Conjugated: FITC/ PE
Species Reactivity: Human
Storage Buffer: PBS, 0,09% sodium Azide, may contain carrier protein-stabilizer
Regulatory Status: RUO

Antigen details

Large description:

Specificity & Reactivity: The CD8 antigen is expressed on the 32-kilodalton (kd) subunit of a disulfide-linked bimolecular complex. The majority of peripheral blood CD8 + T lymphocytes expresses an heterodimer (Mr 32, 30 kd), while CD8 + CD16 + natural killer (NK) lymphocytes and CD8 +T-cell receptor (TCR)+ T lymphocytes express an ?homodimer (Mr 30 kd).

CD56 recognizes an extracellular immunoglobulin-like domain common to three molecular weight forms (Mr 120, 140, and 180 kd) of the neural cell adhesion molecule.

Clinical Applications: The CD8 antigen is present on the human suppressor/cytotoxic T-lymphocyte subset as well as on a subset of NK lymphocytes.15 The CD8 antigen is expressed on 19% to 48% of normal peripheral blood lymphocytes 16 and 60% to 85% of normal thymocytes. The CD56 antigen is present on approximately 10% to 25% of peripheral blood lymphocytes. It is present on essentially all resting and activated CD16 + NK lymphocytes and approximately 5% of CD3 + peripheral blood lymphocytes.