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CD117 - IMMUNOSTEP. WE KNOW HOW

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CD117 - IMMUNOSTEP. WE KNOW HOW

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PURE - anti Human CD117 -

Reference	Size	Price	Quantity	Add to cart
CKITACPO	0,1 mg	225,50 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

CKITACPO

0,1 mg

225,50 € tax excl.

Product Description

Tested Applications: WB
Conjugated: PURE
Species Reactivity: Human
Storage Buffer: PBS, 0,09% sodium Azide, may contain carrier protein-stabilizer
Regulatory Status: RUO

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C-kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also know as stem cell factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K). C-kit is a member of the subfamily of receptor tyrosine kinases (RTK class III ) that includes PDGF, CSF-1 and Flk2.The proto-oncogene c-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Other names: CD117, Mast/stem cell growth factor receptor Kit, SCFR, EC-2.7.10.1, Piebald trait protein, PBT, Proto-oncogene c-Kit, c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

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