LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes, but not neutrophils. Recombinant Human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Source:
E.coli
Synonyms:
Liver-Expressed Chemokine, CCL16, NCC-4, HCC-4, LMC, LCC-1, MTN-1, IL-10-inducible chemokine
AA Sequence:
QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ
Purity:
≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract total human monocytes using a concentration range of 10-100 ng/ml.
