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Anti-F1A alpha Antibody

品牌：Antibodies

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规格：100µl

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Anti-F1A alpha Antibody

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Name:	Anti-F1A alpha Antibody See all F1A alpha primary antibodies
Description:	Rabbit polyclonal antibody to F1A alpha
Applications:	E, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Raised against a peptide corresponding to amino acids 609 to 622 of human F1A alpha. This sequence is identical to the corresponding sequence of mouse FEM1b.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Function:	Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet (By similarity). Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity).
Tissue Specificity:	Present in ***** testis (at protein level).
Sequence Similarities:	Belongs to the fem-1 family.
Cellular locations:	Cytoplasm. Nucleus. Associated with chromatin.
Database Links:	Entrez Gene: 10116?Human Entrez Gene: 14155?Mouse Entrez Gene: 315745?Rat Omim: 613539?Human SwissProt: Q9UK73?Human SwissProt: Q9Z2G0?Mouse SwissProt: P0C6P7?Rat Unigene: 362733?Human Unigene: 24069?Mouse Unigene: 219320?Rat
Synonyms:	F1A alpha Antibody F1A-alpha Antibody F1AA Antibody FEM 1B Antibody Fem-1-like death receptor-binding protein alpha Antibody Fem-1-like in apoptotic pathway protein alpha Antibody Fem1 homolog b Antibody FEM1 like death receptor binding protein Antibody FEM1-beta Antibody FEM1b Antibody FEM1B_HUMAN Antibody Protein fem-1 homolog B Antibody
Information:	Target information shown above is from the UniProt Consortium.