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Anti-ELMO2 Antibody

品牌：Antibodies

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规格：100µg

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应用：

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Anti-ELMO2 Antibody

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Overview

Name:	Anti-ELMO2 Antibody See all ELMO2 primary antibodies
Description:	Goat polyclonal antibody to ELMO2.
Applications:	ELISA, WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human ELMO2 (C terminal).
Sequence:	C-PKEPSSYDFVYHYG
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Tissue Specificity:	Widely expressed, with a higher expression in skeletal muscle, kidney and placenta.
Involvement in Disease:	Vascular malformation, primary intraosseous: A rare malformation characterized by non-neoplastic severe expansions of blood vessels, usually seen in the vertebral column and in the skull. The most commonly affected bones in the skull are the mandible and the maxilla, and life-threatening bleeding after a simple tooth extraction is frequently observed. Inheritance is autosomal recessive.
Cellular locations:	Cytoplasm. Cytoplasm > Cytosol. Membrane.
Database Links:	Entrez Gene: 63916?Human Omim: 606421?Human SwissProt: Q96JJ3?Human Unigene: 210469?Human
Synonyms:	CED 12 Antibody Ced 12 homolog 2 Antibody CED 12 homolog A Antibody CED 12A Antibody CED-12 Antibody ced-12 homolog 2 Antibody CED12 Antibody CED12 homolog A Antibody CED12, C. elegans, homolog of, 2 Antibody CED12A Antibody ELMO 2 Antibody ELMO-2 Antibody ELMO2 Antibody ELMO2_HUMAN Antibody Engulfment and cell motility 2 Antibody Engulfment and cell motility 2 (ced 12 homolog, C. elegans) Antibody Engulfment and cell motility gene 2 Antibody Engulfment and cell motility protein 2 Antibody FLJ11656 Antibody hCED 12A Antibody hCED-12A Antibody hCED12A Antibody KIAA1834 Antibody OTTHUMP00000031762 Antibody PH domain protein CED12A Antibody Protein ced 12 homolog A Antibody Protein ced-12 homolog A Antibody
Information:	Target information shown above is from the UniProt Consortium.