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 Anti-CTCFL Antibody |产品详情|进口榴莲视频官网成人采购网



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Anti-CTCFL Antibody
品牌:Antibodies
货号:
规格:100µl
货期:

Anti-CTCFL Antibody

商品详情 参考文献 相关资料
Name: Anti-CTCFL Antibody
See all CTCFL primary antibodies
Description: Rabbit polyclonal antibody to CTCFL
Specificity: The antibody detects endogenous level of total CTCFL antibody.
Applications: WB, IF
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human CTCFL.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were purified by affinity purification using immunogen.
Concentration: 1.0mg / ml
Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
Tissue Specificity: Testis specific. Specifically expressed in primary spermatocytes.
Sequence Similarities: Belongs to the CTCF zinc-finger protein family.
Cellular locations: Cytoplasm. Nucleus.
Database Links:
  • Entrez Gene: 140690?Human
  • Entrez Gene: 664799?Mouse
  • Entrez Gene: 100360757?Rat
  • Omim: 607022?Human
  • SwissProt: Q8NI51?Human
  • SwissProt: A2APF3?Mouse
  • Unigene: 131543?Human
  • Unigene: 389396?Mouse
  • Synonyms:
  • BORIS Antibody
  • BORIS like protein Antibody
  • Brother of the regulator of imprinted sites Antibody
  • Cancer/testis antigen 27 Antibody
  • CCCTC binding factor (zinc finger protein) like Antibody
  • CCCTC-binding factor Antibody
  • CT27 Antibody
  • CTCF paralog Antibody
  • CTCF T Antibody
  • CTCF-like protein Antibody
  • Ctcfl Antibody
  • CTCFL_HUMAN Antibody
  • dJ579F20.2 Antibody
  • HMG 1L1 Antibody
  • HMGB1L1 Antibody
  • MGC163358 Antibody
  • MGC169105 Antibody
  • MGC169106 Antibody
  • Putative high mobility group protein 1 like 1 Antibody
  • Putative high mobility group protein B1 like 1 Antibody
  • Transcriptional repressor CTCFL Antibody
  • Zinc finger protein CTCF-T Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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