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Anti-COPE Antibody

品牌：Antibodies

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规格：100µl

货期：

应用：

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Anti-COPE Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-COPE Antibody See all COPE primary antibodies
Description:	Rabbit polyclonal antibody to COPE
Specificity:	Human
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Recombinant protein
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity purified
Concentration:	1.0mg / ml
Formulation:	PBS, pH 7.4 with 0.02% Sodium Azide
Storage:	This product is stable for several weeks at 4?C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20?C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Target

Function:	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosesynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Sequence Similarities:	Belongs to the COPE family.
Post-Translational Modification:	Phosphorylated by PKA.
Cellular locations:	Cytoplasm. Golgi apparatus membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Database Links:	Entrez Gene: 11316?Human Omim: 606942?Human SwissProt: O14579?Human Unigene: 10326?Human
Synonyms:	1110005D17Rik Antibody Coatomer epsilon subunit Antibody Coatomer protein complex subunit epsilon Antibody Coatomer subunit epsilon Antibody COPE Antibody Cope1 Antibody COPE_HUMAN Antibody Epsilon coat protein Antibody Epsilon COP Antibody Epsilon COP I Antibody Epsilon subunit of coatomer protein complex Antibody Epsilon-coat protein Antibody Epsilon-COP Antibody FLJ13241 Antibody
Information:	Target information shown above is from the UniProt Consortium.