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Anti-CLC-4 Antibody

品牌：Antibodies

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规格：50µl

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Anti-CLC-4 Antibody

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Overview

Name:	Anti-CLC-4 Antibody See all CLC-4 primary antibodies
Description:	Rabbit polyclonal antibody to CLC-4
Specificity:	CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein.
Applications:	WB, IF, ELISA
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from the Internal region of human CLC-4.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20˚C / 1 year

Target

Function:	Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons.
Tissue Specificity:	Abundant in skeletal muscle and also detectable in brain and heart.
Involvement in Disease:	Mental retardation, X-linked 49: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations.
Sequence Similarities:	Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily.
Cellular locations:	Early endosome membrane. Late endosome membrane. Endoplasmic reticulum membrane.
Database Links:	Entrez Gene: 1183 Human Entrez Gene: 12727 Mouse Entrez Gene: 60586 Rat Omim: 302910 Human SwissProt: P51793 Human SwissProt: Q61418 Mouse SwissProt: P51794 Rat Unigene: 495674 Human Unigene: 297883 Mouse Unigene: 488576 Mouse Unigene: 44406 Rat
Synonyms:	Chloride channel 4 Antibody Chloride channel protein 4 Antibody Chloride channel, voltage sensitive 4 Antibody Chloride transporter ClC-4 Antibody ClC 4A Antibody ClC-4 Antibody CLC4 Antibody ClC4A Antibody CLCN4 Antibody CLCN4_HUMAN Antibody H(+)/Cl(-) exchange transporter 4 Antibody MGC163150 Antibody
Information:	Target information shown above is from the UniProt Consortium.