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Anti-CCL21 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CCL21 Antibody

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Overview

Name:	Anti-CCL21 Antibody See all CCL21 primary antibodies
Description:	Rabbit polyclonal antibody to CCL21
Specificity:	The antibody detects endogenous levels of total CCL21 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human chemokine (C-C motif) ligand 21
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.6mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Tissue Specificity:	Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.
Sequence Similarities:	Belongs to the intercrine beta (chemokine CC) family.
Cellular locations:	Secreted.
Database Links:	Entrez Gene: 6366?Human Omim: 602737?Human SwissProt: O00585?Human Unigene: 57907?Human
Synonyms:	6Ckine Antibody Beta-chemokine exodus-2 Antibody C C motif chemokine ligand 21 Antibody C-C motif chemokine 21 Antibody CCL21 Antibody CCL21_HUMAN Antibody Chemokine (C-C motif) ligand 21 Antibody Chemokine CC motif ligand 21 Antibody CKb9 Antibody ECL Antibody Efficient Chemoattractant for Lymphocytes Antibody SCYA21 Antibody Secondary lymphoid-tissue chemokine Antibody SLC Antibody Small inducible cytokine A21 Antibody Small inducible cytokine subfamily A (Cys-Cys), member 21 Antibody Small-inducible cytokine A21 Antibody TCA4 Antibody UNQ784/PRO1600 Antibody
Information:	Target information shown above is from the UniProt Consortium.