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Anti-Caspase 2 (K152) Antibody

品牌：Antibodies

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规格：50µl

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Anti-Caspase 2 (K152) Antibody

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Name:	Anti-Caspase 2 (K152) Antibody See all Caspase 2 primary antibodies
Description:	Rabbit polyclonal antibody to Caspase 2 (K152)
Specificity:	Caspase 2 (K136) pAb detects endogenous levels of Caspase 2 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 140-180 of Human Caspase 2.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 51 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Tissue Specificity:	Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In *****s, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Sequence Similarities:	Belongs to the peptidase C14A family.
Post-Translational Modification:	The mature protease can process its own propeptide, but not that of other caspases.
Database Links:	Entrez Gene: 835?Human Entrez Gene: 12366?Mouse Entrez Gene: 64314?Rat Omim: 600639?Human SwissProt: P42575?Human SwissProt: P29594?Mouse SwissProt: P55215?Rat Unigene: 368982?Human Unigene: 3921?Mouse Unigene: 488970?Mouse Unigene: 1438?Rat
Synonyms:	CASP-2 Antibody Casp2 Antibody CASP2_HUMAN Antibody Caspase 2 Antibody Caspase-2 subunit p12 Antibody Caspase2 Antibody ICH 1L Antibody ICH1 Antibody ICH1 protease Antibody ICH1L Antibody ICH1L/1S Antibody NEDD-2 Antibody NEDD2 Antibody Neural precursor cell expressed developmentally down-regulated protein 2 Antibody Protease ICH-1 Antibody
Information:	Target information shown above is from the UniProt Consortium.