Anti-CA II (N229) Antibody |产品详情|进口榴莲视频官网成人采购网

您好，欢迎来到榴莲视频成版APP下载生物网站！请登录注册

我的订单 | 联系榴莲视频成版APP下载 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA榴莲视频网站入口、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口榴莲视频官网成人、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于榴莲视频成版APP下载

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海榴莲视频成版APP下载生物科技公司

Tel:400-968-7988 021-33779008

Anti-CA II (N229) Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

应用：

咨询客服

立即购买加入购物车

Anti-CA II (N229) Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-CA II (N229) Antibody See all CA II primary antibodies
Description:	Rabbit polyclonal antibody to CA II (N229)
Specificity:	CA II (N229) pAb detects endogenous levels of CA II protein.
Applications:	WB, IHC
Reactivity:	Human, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 201-250 of Human CA II.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 28 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Target

Function:	Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
Involvement in Disease:	Osteopetrosis, autosomal recessive 3: A rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. Osteopetrosis occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or *****hood. Recessive osteopetrosis commonly manifests in early infancy with macrocephaly, feeding difficulties, evolving blindness and deafness, bone marrow failure, severe anemia, and hepatosplenomegaly. Deafness and blindness are generally thought to represent effects of pressure on nerves. OPTB3 is associated with renal tubular acidosis, cerebral calcification (marble brain disease) and in some cases with mental retardation.
Sequence Similarities:	Belongs to the alpha-carbonic anhydrase family.
Cellular locations:	Cytoplasm. Cell membrane. Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
Database Links:	Entrez Gene: 760?Human Entrez Gene: 54231?Rat Omim: 611492?Human SwissProt: P00918?Human SwissProt: P27139?Rat Unigene: 155097?Human Unigene: 26083?Rat
Synonyms:	CA 2 Antibody CA II Antibody CA-II Antibody Ca2 Antibody CAC Antibody CAH2_HUMAN Antibody CAII Antibody Car 2 Antibody Car2 Antibody Carbonate dehydratase II Antibody Carbonic anhydrase 2 Antibody Carbonic anhydrase B Antibody Carbonic anhydrase C Antibody Carbonic anhydrase C, formerly Antibody Carbonic Anhydrase II Antibody Carbonic dehydratase Antibody epididymis luminal protein 76 Antibody Epididymis secretory protein Li 282 Antibody HEL-76 Antibody HEL-S-282 Antibody
Information:	Target information shown above is from the UniProt Consortium.