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Anti-VDAC2 Antibody

品牌：Antibodies

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规格：100µg

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Anti-VDAC2 Antibody

商品详情参考文献相关资料

Name:	Anti-VDAC2 Antibody See all VDAC2 primary antibodies
Description:	Goat polyclonal antibody to VDAC2.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human VDAC2 (C terminal).
Sequence:	C-GHKVGLALELEA
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
Tissue Specificity:	Expressed in all tissues examined.
Sequence Similarities:	Belongs to the eukaryotic mitochondrial porin family.
Post-Translational Modification:	Ubiquitinated by PARK2 during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
Cellular locations:	Mitochondrion outer membrane.
Database Links:	Entrez Gene: 7417 Human Omim: 193245 Human SwissProt: P45880 Human Unigene: 355927 Human
Synonyms:	B-36 vdac Antibody FLJ23841 Antibody hVDAC2 Antibody OTTHUMP00000019878 Antibody OTTHUMP00000019879 Antibody OTTHUMP00000019880 Antibody Outer mitochondrial membrane protein porin 2 Antibody POR Antibody Porin-2 Antibody VDAC 2 Antibody VDAC-2 Antibody VDAC2 Antibody VDAC2_HUMAN Antibody Vdac6 Antibody Voltage dependent anion channel 2 Antibody Voltage dependent anion selective channel protein 2 Antibody Voltage-dependent anion-selective channel protein 2 Antibody
Information:	Target information shown above is from the UniProt Consortium.