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Anti-CD20 Antibody

品牌：Antibodies

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规格：5ml

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Anti-CD20 Antibody

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Overview

Name:	Anti-CD20 Antibody See all CD20 primary antibodies
Description:	Mouse monoclonal (L26) antibody to CD20.
Specificity:	Human CD20cy on peripheral and lymphoidal B-cells, germ center of lymph nodes.
Applications:	IHC
Reactivity:	Human
Immunogen:	B-Cells from human Tonsils.
Host:	Mouse
Clonality:	Monoclonal
Clone:	L26
Isotype:	IgG2a
Conjugate:	Unconjugated
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.3, with 0.09% Sodium Azide.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes:	This antibody reacts extremly well with B cell lymphoma, in rare cases it may also react with T cell lymphoma. In Non-Hodgkin Lymphoma Reed Sternberg Cells will be stained.

Target

Function:	This protein may be involved in the regulation of B-cell activation and proliferation.
Tissue Specificity:	Expressed on B-cells.
Involvement in Disease:	Immunodeficiency, common variable, 5: A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.
Sequence Similarities:	Belongs to the MS4A family.
Post-Translational Modification:	Phosphorylated. Might be functionally regulated by protein kinase(s).
Cellular locations:	Cell membrane. Cell membrane.
Database Links:	Entrez Gene: 931?Human Omim: 112210?Human SwissProt: P11836?Human Unigene: 712553?Human
Synonyms:	APY Antibody ATOPY Antibody B lymphocyte antigen CD20 Antibody B Lymphocyte Cell Surface Antigen B1 Antibody B-lymphocyte antigen CD20 Antibody B-lymphocyte cell-surface antigen B1 Antibody B-lymphocyte surface antigen B1 Antibody B1 Antibody Bp 35 Antibody Bp35 Antibody CD 20 Antibody CD20 Antibody CD20 antigen Antibody CD20 receptor Antibody CD20_HUMAN Antibody CVID5 Antibody Fc epsilon receptor I beta chain Antibody Fc Fragment of IgE high affinity I receptor for beta polypeptide Antibody FCER1B Antibody High affinity immunoglobulin epsilon receptor subunit beta Antibody IgE Fc receptor subunit beta Antibody IGEL Antibody IGER Antibody IGHER Antibody LEU 16 Antibody LEU16 Antibody leukocyte surface antigen Leu 16 Antibody Leukocyte surface antigen Leu-16 Antibody Ly44 Antibody Membrane spanning 4 domains A1 Antibody Membrane spanning 4 domains subfamily A member 2 Antibody Membrane-spanning 4-domains subfamily A member 1 Antibody MGC3969 Antibody MS4A1 Antibody MS4A2 Antibody S7 Antibody
Information:	Target information shown above is from the UniProt Consortium.