Anti-Pregnancy associated plasma protein A (human, PAPP-A) ABS 006-01 ABS 006-01|产品详情|进口榴莲视频官网成人采购网

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Anti-Pregnancy associated plasma protein A (human, PAPP-A) ABS 006-01

品牌：

货号：ABS 006-01

规格：200 µg

货期：

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Anti-Pregnancy associated plasma protein A (human, PAPP-A)

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Cat. No.: ABS 006-01
Product name: Anti-Pregnancy associated plasma protein A (human, PAPP-A)
Description: Mouse monoclonal antibody
Specificity: ABS 006-01 is specific for native human PAPP-A
Immunogen: Purified human PAPP-A
Application: ELISA, WB, IHC
Species reactivity (positive): Human
Species reactivity (negative): Not determined
Subclass: IgG1/k
Gene ID: 5069
Clone number: PAPP A 1-1
Epitope: The epitope of ABS 006-01 is different from BTE 004-09 and ABS 001-24. The epitope is located on the PAPP-A subunit of the heterotetramer.
Content: Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification: Protein-A purified
Form: Liquid
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
Target: Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down’s syndrome (trisomy 21).

Application 1: ELISA
In sandwich ELISA with a polyclonal antibody in coat, ABS 006-01 only reacts poorly with PAPP-A in third trimester serum.
Application 2: WB
ABS 006-01 only detects unreduced PAPP-A in Western blotting.
Application 3: IHC
ABS 006-01 can be used in IHC. Please consult www.proteinatlas.org

Paraffin-embedded human placenta tissue immunostained with ABS 006-01 (www.proteinatlas.org)

Immunohistochemical staining of a formalin-fixed, paraffin-embedded placental tissue with ABS 006-01